SCHEMBL1667085

SCHEMBL1667085

O=C(C1=C(C(=O)c2ccccc2)C(C(=O)c2ccccc2)c2cccc3cccc1c23)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.44
HTT P42858 3/20 0.44
ALOX15 P16050 1/20 0.44
HBB P68871 1/20 0.44
EPHX1 P07099 1/20 0.40
KMT2A Q03164 6/20 0.36
L3MBTL1 Q9Y468 5/20 0.36
MEN1 O00255 5/20 0.36
ALDH1A1 P00352 4/20 0.36
LMNA P02545 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
NPSR1 Q6W5P4 3/20 0.36
XBP1 P17861 1/20 0.36
HKDC1 Q2TB90 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
ATM Q13315 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1669230 0.82 EPHX1 (0.36) MAPTHTTALOX15HBBEPHX1
SCHEMBL1669188 0.77 ALDH1A1 (0.50) MAPTHTTALOX15KMT2AL3MBTL1
SCHEMBL1666386 0.72 EPHX1 (0.40) MAPTHTTALOX15HBBEPHX1
SCHEMBL10556752 0.69 MAPT (0.64) MAPTHTTALOX15HBBEPHX1
SCHEMBL1666408 0.67 HSD17B10 (0.41) MAPTHTTKMT2AL3MBTL1MEN1
SCHEMBL10865331 0.67 HTT (0.35) MAPTHTTALOX15KMT2AL3MBTL1
SCHEMBL10611039 0.66 HSD17B10 (0.43) MAPTHTTALOX15HBBKMT2A
Pyrene SCHEMBL27886107 0.66 ALDH1A1 (0.67) MAPTKMT2AL3MBTL1MEN1ALDH1A1
SCHEMBL1666454 0.65 ALDH1A1 (0.39) MAPTALOX15KMT2AL3MBTL1MEN1
SCHEMBL2850467 0.64 EPHX1 (0.37) MAPTHTTALOX15HBBEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1830228-B1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2015-08-05 EP disclosed
EP-2808736-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-03 EP disclosed
US-8802353-B2 Compound for resist and radiation-sensitive composition specification MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-08-12 US disclosed
EP-2662727-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-11-13 EP disclosed
US-8350096-B2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-01-08 US disclosed
US-20130004896-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION SPECIFICATION ECHIGO MASATOSHI (JP) 2013-01-03 US disclosed
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION ECHIGO MASATOSHI 2011-07-07 US disclosed
US-7919223-B2 Polyphenol compound synthesized by condensation between aromatic ketone or aldehyde and a phenol; acid-amplified, non-polymeric resist; highly sensitive to KrF excimer lasers, extreme ultraviolet rays, electron beams, X-rays; resist patterns with high resolution, high heat, etch resistance MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-04-05 US disclosed
US-20080113294-A1 Compound for Resist and Radiation-Sensitive Composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-05-15 US disclosed
EP-1830228-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION XRCC6, XRCC5, KISS1R MAPT 1377/4885HTT 2797/4885ALOX15 2727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.