SCHEMBL1669188

SCHEMBL1669188

O=C(C1=C(C(=O)c2ccccc2)c2cccc3cccc1c23)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
L3MBTL1 Q9Y468 4/20 0.48
ATM Q13315 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
HSD17B10 Q99714 5/20 0.48
TSHR P16473 2/20 0.48
MAPK1 P28482 2/20 0.48
KMT2A Q03164 6/20 0.47
MEN1 O00255 5/20 0.47
LMNA P02545 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
NPSR1 Q6W5P4 3/20 0.47
XBP1 P17861 1/20 0.47
HKDC1 Q2TB90 1/20 0.47
CES2 O00748 1/20 0.45
BCHE P06276 1/20 0.45
CES1 P23141 1/20 0.45
MCL1 Q07820 1/20 0.45
CARM1 Q86X55 1/20 0.45
KDM4E B2RXH2 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1666408 0.84 HSD17B10 (0.41) ALDH1A1L3MBTL1ATMTDP1HSD17B10
SCHEMBL901091 0.79 HSD17B10 (0.59) ALDH1A1L3MBTL1ATMTDP1HSD17B10
Pyrene SCHEMBL27886107 0.79 ALDH1A1 (0.67) ALDH1A1L3MBTL1ATMTDP1HSD17B10
SCHEMBL1667018 0.78 L3MBTL1 (0.43) ALDH1A1L3MBTL1ATMTDP1MAPK1
SCHEMBL1667085 0.77 MAPT (0.44) ALDH1A1L3MBTL1ATMTDP1HSD17B10
Benzophenone SCHEMBL15756048 0.73 ALDH1A1 (0.82) ALDH1A1L3MBTL1ATMTDP1TSHR
SCHEMBL1666908 0.72 ALDH1A1 (0.57) ALDH1A1L3MBTL1ATMHSD17B10TSHR
SCHEMBL29001210 0.72 MEN1 (0.72) ALDH1A1L3MBTL1ATMTDP1HSD17B10
SCHEMBL30403497 0.72 MEN1 (0.52) ALDH1A1L3MBTL1ATMTDP1TSHR
SCHEMBL23300519 0.72 ALDH1A1 (0.47) ALDH1A1L3MBTL1ATMTDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1830228-B1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2015-08-05 EP disclosed
EP-2808736-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-03 EP disclosed
US-8802353-B2 Compound for resist and radiation-sensitive composition specification MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-08-12 US disclosed
EP-2662727-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-11-13 EP disclosed
US-8350096-B2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-01-08 US disclosed
US-20130004896-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION SPECIFICATION ECHIGO MASATOSHI (JP) 2013-01-03 US disclosed
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION ECHIGO MASATOSHI 2011-07-07 US disclosed
CN-101088046-B Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO 2011-05-25 CN disclosed
US-7919223-B2 Polyphenol compound synthesized by condensation between aromatic ketone or aldehyde and a phenol; acid-amplified, non-polymeric resist; highly sensitive to KrF excimer lasers, extreme ultraviolet rays, electron beams, X-rays; resist patterns with high resolution, high heat, etch resistance MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-04-05 US disclosed
US-20080113294-A1 Compound for Resist and Radiation-Sensitive Composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-05-15 US disclosed
CN-101088046-A Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO (JP) 2007-12-12 CN disclosed
EP-1830228-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION XRCC6, XRCC5, KISS1R ALDH1A1 1170/4885L3MBTL1 2904/4885ATM 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.