Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.64 |
| ▸ | SHBG | P04278 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13558385 | 1.00 | LMNA (0.74) | LMNAMAPTNR3C1MEN1KMT2A | |
| SCHEMBL10380227 | 0.91 | LMNA (0.74) | LMNAMAPTNR3C1MEN1KMT2A | |
| SCHEMBL13558392 | 0.90 | LMNA (0.73) | LMNAMAPTNR3C1MEN1KMT2A | |
| SCHEMBL5172933 | 0.88 | HSD17B10 (0.74) | LMNAMAPTNR3C1MEN1KMT2A | |
| SCHEMBL21242937 | 0.88 | HSD17B10 (0.74) | LMNAMAPTNR3C1MEN1KMT2A | |
| SCHEMBL11586130 | 0.88 | LMNA (0.70) | LMNAMAPTNR3C1MEN1KMT2A | |
| SCHEMBL19242588 | 0.88 | HSD17B10 (0.74) | LMNAMAPTNR3C1MEN1KMT2A | |
| SCHEMBL12738227 | 0.87 | LMNA (0.72) | LMNAMAPTNR3C1MEN1KMT2A | |
| SCHEMBL11208456 | 0.87 | LMNA (0.72) | LMNAMAPTNR3C1MEN1KMT2A | |
| SCHEMBL10414421 | 0.87 | LMNA (0.69) | LMNAMAPTNR3C1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057401-A1 | Aromatic heterocyclic esters of steroids, their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-08-11 | — | — | EP | claimed |
| JP-57088197-A | — | — | None | — | — | JP | disclosed |
| US-20190038637-A1 | Use of Hydroxyprogesterone Derivatives for Enhanced Health and Physical Performance II | MARCHEWITZ ERIC (US) | 2019-02-07 | — | — | US | disclosed |
| US-20120277201-A1 | Use of hydroxyprogesterone derivatives for enhancing health and physical performance | MARCHEWITZ ERIC D (US) | 2012-11-01 | — | — | US | disclosed |
| US-4585591-A | 17β-ethynylsteroids and process for preparing same | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1986-04-29 | — | — | US | disclosed |
| EP-0053845-B1 | 17-BETA-ETHYNYLSTEROIDS AND PROCESS FOR PREPARING SAME | MITSUBISHI KASEI CORPORATION (JP) | 1985-04-10 | — | — | EP | disclosed |
| US-4472393-A | ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1984-09-18 | — | — | US | disclosed |
| EP-0053845-A1 | 17-Beta-ethynylsteroids and process for preparing same | MITSUBISHI KASEI CORPORATION (JP) | 1982-06-16 | — | — | EP | disclosed |
| JP-S5788197-A | PREPARATION OF SYNTHETIC INTERMEDIATE OF CORTICOIDS | MITSUBISHI CHEM IND LTD | 1982-06-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277201-A1 | Use of hydroxyprogesterone derivatives for enhancing health and physical performance | HSD17B11, HSD17B1, CYP19A1 | LMNA 2630/4885MAPT 2314/4885NR3C1 58/4885 |
| US-20190038637-A1 | Use of Hydroxyprogesterone Derivatives for Enhanced Health and Physical Performance II | HSD17B11, HSD17B2, HSD17B1 | LMNA 2511/4885MAPT 3159/4885NR3C1 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.