Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | BRD1 | O95696 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10830968 | 0.82 | CASP1 (0.43) | HTTKMT2AALDH1A1CASP1TSHR | |
| SCHEMBL10864818 | 0.78 | P2RX4 (0.47) | SMN1; SMN2HTTPOLBRXFP1L3MBTL1 | |
| SCHEMBL5682777 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTPOLBRXFP1L3MBTL1 | |
| SCHEMBL10812530 | 0.74 | KMT2A (0.38) | SMN1; SMN2POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL5654777 | 0.74 | TDP1 (0.42) | SMN1; SMN2HTTPOLBL3MBTL1MEN1 | |
| SCHEMBL10865100 | 0.71 | MAPT (0.44) | HTTMEN1APEX1KMT2AALDH1A1 | |
| SCHEMBL10864869 | 0.71 | CASP1 (0.50) | SMN1; SMN2HTTL3MBTL1MEN1KMT2A | |
| SCHEMBL10864378 | 0.71 | CASP1 (0.44) | SMN1; SMN2MEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL31259927 | 0.71 | ALDH1A1 (0.41) | SMN1; SMN2HTTPOLBKMT2AALDH1A1 | |
| SCHEMBL38653310 | 0.70 | ALPL (0.48) | ALDH1A1TDP1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074595-B1 | SUBSTITUTED PHENYLSULFONYL UREA DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-07-23 | — | — | EP | claimed |
| EP-0074595-B1 | SUBSTITUTED PHENYLSULFONYL UREA DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-07-23 | — | — | EP | disclosed |
| US-4545944-A | Herbicidally active novel substituted phenylsulfonylurea derivatives and intermediates therefor | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-10-08 | — | — | US | disclosed |
| US-4474600-A | Herbicidally active novel substituted phenylsulfonylurea derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-10-02 | — | — | US | disclosed |
| EP-0074595-A1 | Substituted phenylsulfonyl urea derivatives, process and intermediates for their preparation, and their use as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-03-23 | — | — | EP | disclosed |