Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.38 |
| ▸ | FEN1 | P39748 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9591445 | 0.82 | KDM4E (0.58) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10867729 | 0.78 | SMN1; SMN2 (0.36) | KDM4EMEN1KMT2AUSP2POLB | |
| SCHEMBL10865751 | 0.78 | KDM4E (0.39) | KDM4EALOX5APFEN1MEN1KMT2A | |
| SCHEMBL9588686 | 0.78 | CA1 (0.48) | KDM4EMEN1KMT2AHSD17B10L3MBTL1 | |
| SCHEMBL9742404 | 0.77 | HCRTR1 (0.43) | KDM4EMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL9741957 | 0.77 | SMN1; SMN2 (0.55) | KDM4EMEN1KMT2APOLBTSHR | |
| SCHEMBL10498917 | 0.74 | KDM4E (0.54) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9833941 | 0.74 | ALDH1A1 (0.43) | ALOX5APFEN1MEN1KMT2ATSHR | |
| SCHEMBL9833936 | 0.74 | ALDH1A1 (0.43) | ALOX5APFEN1MEN1KMT2ATSHR | |
| SCHEMBL9735397 | 0.74 | SMN1; SMN2 (0.69) | KDM4EMEN1KMT2ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5092917-A | HERBICIDAL AMINOGUANIDINOAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | claimed |
| US-5217522-A | HERBICIDAL SULPHONYLGUANIDINOAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | disclosed |
| US-5211740-A | Applying triazinyl sulfonylguanidine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-18 | — | — | US | disclosed |
| US-5211740-A | Applying triazinyl sulfonylguanidine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-18 | — | — | US | disclosed |
| EP-0507172-A1 | Sulfonylguanidinoazines | BAYER AG (DE) | 1992-10-07 | — | — | EP | disclosed |
| US-5092917-A | HERBICIDAL AMINOGUANIDINOAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5092917-A | HERBICIDAL AMINOGUANIDINOAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| EP-0343462-A1 | Aminoguanidino azines | BAYER AG (DE) | 1989-11-29 | — | — | EP | disclosed |