SCHEMBL1086578

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1086784	0.85	TSHR (0.38)	USP2CYP2C9CYP1A2CYP2C19CYP2D6
	SCHEMBL1086351	0.85	CYP2D6 (0.50)	USP2CYP2C9CYP1A2CYP2C19CYP2D6
	SCHEMBL1086423	0.83	TACR2 (0.39)	GRM2
	SCHEMBL1086310	0.83	GRIN1 (0.37)	USP2CYP2C9CYP1A2CYP2C19CYP2D6
	SCHEMBL1085970	0.83	HSD11B1 (0.44)	CYP2C9CYP2C19GRM2MEN1KMT2A
	SCHEMBL1086534	0.80	FKBP1A (0.48)	ALDH1A1TSHRGRM2MEN1KMT2A
	SCHEMBL1086117	0.78	RIPK1 (0.42)	USP2CYP2C9CYP1A2CYP2C19CYP2D6
	SCHEMBL1086300	0.78	HTT (0.38)	CYP2C9CYP2C19ALDH1A1
	SCHEMBL1086551	0.78	TACR1 (0.42)	EPHX2GRM2HCRTR1HCRTR2MEN1
	SCHEMBL1086092	0.78	RIPK1 (0.39)	USP2CYP2C9EPHX2ALDH1A1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.