Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408653 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL10506559 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL10510895 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL7995469 | 0.75 | SMN1; SMN2 (0.64) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL7995471 | 0.75 | SMN1; SMN2 (0.64) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL9408588 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL9408700 | 0.73 | KCNJ1 (0.42) | SMN1; SMN2 | |
| SCHEMBL10573632 | 0.72 | SMN1; SMN2 (0.36) | SMN1; SMN2CHRNA1CHRNA3CHRNA7 | |
| SCHEMBL9408578 | 0.72 | SMN1; SMN2 (0.34) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL10672935 | 0.71 | CACNA1G (0.34) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61267561-A | — | — | None | — | — | JP | disclosed |
| JP-S61267561-A | NITROMETHYLENE DERIVATIVE, INTERMEDIATE THEREFOR, PRODUCTION THEREOF AND INSECTICIDE | NIPPON TOKUSHU NOYAKU SEIZO KK | 1986-11-27 | — | — | JP | disclosed |