Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408653 | 0.81 | SMN1; SMN2 (0.41) | KCNH2ALDH1A1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL9408716 | 0.80 | KCNJ1 (0.42) | KCNJ1KCNH2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9408705 | 0.79 | SMN1; SMN2 (0.54) | KCNJ1KCNH2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL10614293 | 0.79 | SMN1; SMN2 (0.54) | KCNJ1KCNH2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9408711 | 0.76 | CHRNA1 (0.56) | KCNJ1KCNH2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9408715 | 0.74 | KCNJ1 (0.41) | KCNJ1KCNH2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL10867211 | 0.73 | SMN1; SMN2 (0.38) | SMN1; SMN2 | |
| SCHEMBL9408578 | 0.72 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL10510895 | 0.71 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7359643 | 0.68 | CYP19A1 (0.52) | KCNH2CYP19A1CYP11B1CYP11B2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623601-A1 | N-(3-Fluorobenzyl)heterocyclic derivatives and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1994-11-09 | — | — | EP | disclosed |