Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.31 |
| ▸ | RXRB | P28702 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1087391 | 0.92 | RAPGEF4 (0.49) | RAPGEF4HTR1DHTR1BTNIKAPP | |
| SCHEMBL6131646 | 0.84 | AKR1C3 (0.39) | RAPGEF4ACP1AKR1C3AKR1C2MAPKAPK2 | |
| SCHEMBL1086767 | 0.83 | RAPGEF4 (0.54) | RAPGEF4HTR1DHTR1BAGPAT2APP | |
| SCHEMBL31013582 | 0.77 | AKR1C3 (0.44) | AKR1C3AKR1C2 | |
| SCHEMBL10002566 | 0.76 | RAPGEF4 (0.44) | RAPGEF4AKR1C3AKR1C2MAPKAPK2APP | |
| SCHEMBL14981045 | 0.75 | RAPGEF4 (0.59) | RAPGEF4HTR1DHTR1BPOLB | |
| SCHEMBL30675131 | 0.73 | ALDH1A1 (0.50) | ACP1AKR1C3AKR1C2MAPKAPK2 | |
| SCHEMBL26877419 | 0.73 | ALDH1A1 (0.50) | ACP1AKR1C3AKR1C2MAPKAPK2 | |
| SCHEMBL1087390 | 0.73 | RAPGEF4 (0.55) | RAPGEF4HTR1DHTR1BAGPAT2 | |
| SCHEMBL31013596 | 0.72 | HSD17B2 (0.44) | RXRBRXRAAKR1C3AKR1C2MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153276-B2 | Polymer compound and polymer light emitting device using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-10 | — | — | US | disclosed |