Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.56 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11124942 | 0.92 | REN (0.43) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL10636524 | 0.89 | CTSK (0.54) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL10522069 | 0.87 | ACE (0.57) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL7300127 | 0.87 | ACE (0.57) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL23598225 | 0.87 | ACE (0.57) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL9551311 | 0.85 | REN (0.64) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL9551282 | 0.85 | CTSS (0.54) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL10420805 | 0.85 | CTSS (0.54) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL9876266 | 0.85 | CTSS (0.54) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL27335662 | 0.85 | CTSS (0.54) | RENCTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4548926-A | RENIN INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1985-10-22 | — | — | US | disclosed |
| EP-0128762-A2 | New hypotensive peptides, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1984-12-19 | — | — | EP | disclosed |