Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10867916 | 0.84 | KMT2A (0.51) | ATMTDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL9399530 | 0.83 | ATM (0.49) | ATMTDP1L3MBTL1MAPK8MAPK9 | |
| SCHEMBL9848710 | 0.82 | ATM (0.48) | ATMTDP1L3MBTL1MAPK8MAPK9 | |
| SCHEMBL7317433 | 0.81 | TDP1 (0.61) | TDP1L3MBTL1KDM4EALDH1A1MTNR1A | |
| SCHEMBL10868045 | 0.79 | ALDH1A1 (0.48) | TDP1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8871911 | 0.75 | TDP1 (0.54) | TDP1L3MBTL1KDM4EMTNR1AMEN1 | |
| SCHEMBL29503119 | 0.75 | L3MBTL1 (0.68) | ATMTDP1L3MBTL1MAPK8MAPK9 | |
| SCHEMBL709403 | 0.75 | L3MBTL1 (0.68) | ATMTDP1L3MBTL1MAPK8MAPK9 | |
| Methoxymethane SCHEMBL11047646 | 0.74 | MAPT (0.61) | ATMTDP1KDM4EALDH1A1MTNR1A | |
| SCHEMBL29277098 | 0.74 | KMT2A (0.50) | ATMTDP1L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438873-A1 | Inhibitor of ribonucleotide reductase of herpes viruses | MERCK & CO. INC. (US) | 1991-07-31 | — | — | EP | disclosed |