Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10869109 | 0.92 | HPGD (0.36) | HPGDMGLLHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL10872556 | 0.91 | HPGD (0.36) | HPGDMGLLHTR2AHTR2CHTR2B | |
| SCHEMBL10868610 | 0.82 | HTR1D (0.34) | HPGDMGLLPOLBHTR2AHTR2C | |
| SCHEMBL10867472 | 0.82 | HTR1D (0.34) | HPGDMGLLPOLBHTR2AHTR2C | |
| SCHEMBL10868989 | 0.82 | HTR1D (0.34) | HPGDMGLLPOLBHTR2AHTR2C | |
| SCHEMBL10874542 | 0.81 | HPGD (0.49) | HPGDHTR2AMEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL10867280 | 0.81 | HPGD (0.48) | HPGDHTR2AMEN1KMT2ACYP1A2 | |
| SCHEMBL10869604 | 0.80 | MTNR1A (0.45) | HTR2AKCNH2MEN1KMT2AHTR1A | |
| SCHEMBL10870856 | 0.80 | MPO (0.52) | MGLLHTR1A | |
| SCHEMBL10867739 | 0.80 | HTR1A (0.46) | HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187122-A2 | 1,3,4-Trisubstituted azacycloalkanes or azacycloalkenes | CIBA-GEIGY AG (CH) | 1986-07-09 | — | — | EP | claimed |