Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL10868076

CC(C)(CC(=O)O)C(=O)O.N.N

nearest known ligand 0.57

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
CYP2C19 P33261 2/20 0.57
HIF1A Q16665 2/20 0.57
CYP2D6 P10635 1/20 0.57
HMGCR P04035 1/20 0.52
CHRM1 P11229 1/20 0.52
TBXA2R P21731 1/20 0.52
ADRA1A P35348 1/20 0.52
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 2/20 0.46
CPT2 P23786 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
FFAR1 O14842 1/20 0.44
ACLY P53396 4/20 0.38
ACACB O00763 1/20 0.37
ACACA Q13085 1/20 0.37
TET2 Q6N021 1/20 0.36
FFAR3 O14843 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL10870096 1.00 TSHR (0.57) TSHRCYP2C19HIF1ACYP2D6HMGCR
SCHEMBL83915 0.97 TSHR (0.60) TSHRCYP2C19HIF1ACYP2D6HMGCR
Hydrochloric Acid SCHEMBL4137653 0.97 TSHR (0.60) TSHRCYP2C19HIF1ACYP2D6HMGCR
SCHEMBL6739451 0.94 TSHR (0.57) TSHRCYP2C19HIF1ACYP2D6HMGCR
SCHEMBL28478983 0.94 TSHR (0.57) TSHRCYP2C19HIF1ACYP2D6HMGCR
SCHEMBL8844260 0.94 TSHR (0.57) TSHRCYP2C19HIF1ACYP2D6HMGCR
Water SCHEMBL14109455 0.92 TSHR (0.55) TSHRCYP2C19HIF1ACYP2D6HMGCR
Cyclohexane SCHEMBL11773704 0.89 CYP2C19 (0.52) TSHRCYP2C19HIF1ACYP2D6HMGCR
Succinic Acid SCHEMBL5567772 0.89 CYP2C19 (0.52) TSHRCYP2C19HIF1ACYP2D6HMGCR
SCHEMBL20525263 0.85 CYP2C19 (0.48) TSHRCYP2C19HIF1ACYP2D6HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0178903-A2 Improved tellurium imaging composition and film including imide or ammonium salt ENERGY CONVERSION DEVICES, INC. (US) 1986-04-23 EP claimed
EP-0178903-A2 Improved tellurium imaging composition and film including imide or ammonium salt ENERGY CONVERSION DEVICES, INC. (US) 1986-04-23 EP disclosed
EP-0101887-A2 Cosmetic compositions comprising an aqueous solution of an urea compound, hair treatment, skin moisturizer, hair waving system, retardation of alkali production, and hair and skin treatment methods Helene Curtis Industries, Inc. (US) 1984-03-07 EP disclosed