SCHEMBL6739451

SCHEMBL6739451

CC(C)(CC(=O)O)C(=O)O.[Ag]

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
CYP2C19 P33261 2/20 0.57
HIF1A Q16665 2/20 0.57
CYP2D6 P10635 1/20 0.57
HMGCR P04035 1/20 0.52
CHRM1 P11229 1/20 0.52
TBXA2R P21731 1/20 0.52
ADRA1A P35348 1/20 0.52
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 2/20 0.46
CPT2 P23786 2/20 0.44
FFAR1 O14842 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ACLY P53396 4/20 0.38
ACACB O00763 1/20 0.37
ACACA Q13085 1/20 0.37
TET2 Q6N021 1/20 0.36
FFAR3 O14843 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL83915 0.97 TSHR (0.60) TSHRCYP2C19HIF1ACYP2D6HMGCR
Hydrochloric Acid SCHEMBL4137653 0.97 TSHR (0.60) TSHRCYP2C19HIF1ACYP2D6HMGCR
Ammonia Solution, Strong SCHEMBL10870096 0.94 TSHR (0.57) TSHRCYP2C19HIF1ACYP2D6HMGCR
SCHEMBL8844260 0.94 TSHR (0.57) TSHRCYP2C19HIF1ACYP2D6HMGCR
Ammonia Solution, Strong SCHEMBL10868076 0.94 TSHR (0.57) TSHRCYP2C19HIF1ACYP2D6HMGCR
SCHEMBL28478983 0.94 TSHR (0.57) TSHRCYP2C19HIF1ACYP2D6HMGCR
Water SCHEMBL14109455 0.92 TSHR (0.55) TSHRCYP2C19HIF1ACYP2D6HMGCR
Cyclohexane SCHEMBL11773704 0.89 CYP2C19 (0.52) TSHRCYP2C19HIF1ACYP2D6HMGCR
Succinic Acid SCHEMBL5567772 0.89 CYP2C19 (0.52) TSHRCYP2C19HIF1ACYP2D6HMGCR
SCHEMBL20525263 0.85 CYP2C19 (0.48) TSHRCYP2C19HIF1ACYP2D6HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686133-B2 CONTAINING LIGHT-INSENSITIVE SILVER SALTS OF ORGANIC CARBOXYLIC ACIDS WITH ONE OR MORE CARBOXYLIC ACID AND A BINDER, EXCLUSIVE OF SILVER SUCCINATE SIMILAR COMPOUNDS AGFA-GEVAERT (BE) 2004-02-03 US disclosed