SCHEMBL20525263

SCHEMBL20525263

C/C(C(=O)O)=C(/C)C(=O)O.CC(C)(CC(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.48
HIF1A Q16665 2/20 0.48
TSHR P16473 2/20 0.48
CYP2D6 P10635 1/20 0.48
HMGCR P04035 1/20 0.44
CHRM1 P11229 1/20 0.44
TBXA2R P21731 1/20 0.44
ADRA1A P35348 1/20 0.44
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 2/20 0.39
CPT2 P23786 2/20 0.38
FFAR1 O14842 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ACLY P53396 4/20 0.37
TET2 Q6N021 1/20 0.35
ACACB O00763 1/20 0.32
ACACA Q13085 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4137653 0.87 TSHR (0.60) CYP2C19HIF1ATSHRCYP2D6HMGCR
SCHEMBL83915 0.87 TSHR (0.60) CYP2C19HIF1ATSHRCYP2D6HMGCR
Ammonia Solution, Strong SCHEMBL10870096 0.85 TSHR (0.57) CYP2C19HIF1ATSHRCYP2D6HMGCR
Ammonia Solution, Strong SCHEMBL10868076 0.85 TSHR (0.57) CYP2C19HIF1ATSHRCYP2D6HMGCR
SCHEMBL8844260 0.85 TSHR (0.57) CYP2C19HIF1ATSHRCYP2D6HMGCR
SCHEMBL28478983 0.85 TSHR (0.57) CYP2C19HIF1ATSHRCYP2D6HMGCR
SCHEMBL6739451 0.85 TSHR (0.57) CYP2C19HIF1ATSHRCYP2D6HMGCR
Water SCHEMBL14109455 0.82 TSHR (0.55) CYP2C19HIF1ATSHRCYP2D6HMGCR
Cyclohexane SCHEMBL11773704 0.80 CYP2C19 (0.52) CYP2C19HIF1ATSHRCYP2D6HMGCR
Succinic Acid SCHEMBL5567772 0.80 CYP2C19 (0.52) CYP2C19HIF1ATSHRCYP2D6HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3413134-B1 HYBRID TONER COMPOSITIONS XEROX CORP (US) 2021-12-22 EP disclosed
US-11048184-B2 Toner process employing dual chelating agents XEROX CORPORATION (US) 2021-06-29 US disclosed
US-20200225598-A1 Toner Process Employing Dual Chelating Agents XEROX CORPORATION 2020-07-16 US disclosed
EP-3413134-A1 HYBRID TONER COMPOSITIONS Xerox Corporation (US) 2018-12-12 EP disclosed
US-10095143-B1 Hybrid toner compositions XEROX CORPORATION (US) 2018-10-09 US disclosed