Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10868779 | 1.00 | REN (0.53) | RENBACE1 | |
| SCHEMBL10867881 | 0.93 | KMT2A (0.49) | REN | |
| SCHEMBL28353211 | 0.86 | LMNA (0.52) | REN | |
| SCHEMBL30690971 | 0.86 | LMNA (0.52) | REN | |
| SCHEMBL21877879 | 0.79 | CAPN1 (0.49) | REN | |
| SCHEMBL21877878 | 0.79 | CAPN1 (0.49) | REN | |
| SCHEMBL10868224 | 0.79 | REN (0.58) | REN | |
| SCHEMBL10868254 | 0.79 | REN (0.58) | REN | |
| SCHEMBL24096321 | 0.78 | CA2 (0.51) | — | |
| SCHEMBL10873238 | 0.77 | CAPN1 (0.61) | RENBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186977-A2 | Renin-inhibitory dipeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1986-07-09 | — | — | EP | disclosed |