SCHEMBL10869201

SCHEMBL10869201

C=CC(=O)OC(CCCCC)OOC(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.41
ALDH1A1 P00352 2/20 0.41
THRA P10827 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 3/20 0.38
F2 P00734 1/20 0.38
PRSS1 P07477 3/20 0.38
CTSG P08311 2/20 0.38
CTRB1 P17538 2/20 0.38
CMA1 P23946 2/20 0.38
CTSK P43235 1/20 0.37
CES2 O00748 2/20 0.37
CES1 P23141 2/20 0.37
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
FPR2 P25090 2/20 0.36
TSHR P16473 2/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10868641 0.99 THRB (0.43) THRBALDH1A1THRAMEN1KMT2A
SCHEMBL10868855 0.99 THRB (0.43) THRBALDH1A1THRAMEN1KMT2A
SCHEMBL10868715 0.99 THRB (0.43) THRBALDH1A1THRAMEN1KMT2A
SCHEMBL10870169 0.99 THRB (0.43) THRBALDH1A1THRAMEN1KMT2A
SCHEMBL10868369 0.99 THRB (0.43) THRBALDH1A1THRAMEN1KMT2A
SCHEMBL10869051 0.96 MEN1 (0.40) THRBALDH1A1THRAMEN1KMT2A
SCHEMBL1247172 0.91 LMNA (0.41) THRBALDH1A1THRAMEN1KMT2A
SCHEMBL888080 0.89 THRB (0.46) THRBALDH1A1THRAMEN1KMT2A
SCHEMBL10869832 0.86 LMNA (0.43) THRBALDH1A1MEN1KMT2ALMNA
SCHEMBL3277426 0.86 LMNA (0.48) ALDH1A1MEN1KMT2ALMNAF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110007499-B Multifunctional liquid crystal dimming film with multiple responsibilities, light-transmitting piece and preparation method thereof 北京大学 2021-09-28 CN disclosed
CN-108957825-B Trans-electric control dimming film capable of adjusting near-infrared light transmittance and preparation method thereof 北京大学 2021-05-18 CN disclosed
CN-109752893-B Temperature control light adjusting film for sectionally regulating and controlling visible light and near infrared light transmissivity and preparation method thereof 北京大学 2021-02-02 CN disclosed
CN-107015394-B Trans-electric control dimming film with near infrared light shielding function and preparation method thereof 北京大学 2020-06-26 CN disclosed
EP-0184482-A1 Thermotropical polymers with chiral lateral chains, and process for their preparation THOMSON-CSF (FR) 1986-06-11 EP disclosed