Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 16/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341533 | 0.82 | DGAT1 (0.55) | DGAT1HSD11B1 | |
| SCHEMBL10341501 | 0.74 | DGAT1 (0.42) | DGAT1HSD11B1MAOB | |
| SCHEMBL10923016 | 0.73 | DGAT1 (0.44) | DGAT1 | |
| SCHEMBL9588878 | 0.73 | CYP11B2 (0.47) | — | |
| SCHEMBL10341554 | 0.72 | DGAT1 (0.45) | DGAT1MAOAMAOB | |
| SCHEMBL4495829 | 0.70 | KDM1A (0.42) | DGAT1HSD11B1 | |
| SCHEMBL4495832 | 0.70 | KDM1A (0.42) | DGAT1HSD11B1 | |
| SCHEMBL10341534 | 0.70 | SMN1; SMN2 (0.40) | MAOAMAOB | |
| SCHEMBL10366670 | 0.70 | DGAT1 (0.45) | DGAT1PPARDPPARA | |
| SCHEMBL15748671 | 0.68 | DGAT1 (0.48) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181145-A2 | Heterocyclic compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-05-14 | — | — | EP | disclosed |