Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587982 | 0.82 | LMNA (0.60) | MAPK1LMNAALDH1A1HTTGAA | |
| SCHEMBL13803755 | 0.82 | LMNA (0.84) | MAPK1LMNAALDH1A1HTTGAA | |
| SCHEMBL7365405 | 0.81 | LMNA (0.68) | MAPK1LMNAALDH1A1HTTGAA | |
| SCHEMBL7365408 | 0.81 | LMNA (0.68) | MAPK1LMNAALDH1A1HTTGAA | |
| SCHEMBL5487375 | 0.81 | LMNA (0.72) | LMNAALDH1A1HTTGAASMN1; SMN2 | |
| SCHEMBL5487379 | 0.81 | LMNA (0.72) | LMNAALDH1A1HTTGAASMN1; SMN2 | |
| SCHEMBL21851960 | 0.81 | LMNA (0.68) | MAPK1LMNAALDH1A1HTTGAA | |
| SCHEMBL7306504 | 0.80 | LMNA (0.58) | MAPK1LMNAALDH1A1HTTGAA | |
| SCHEMBL10860393 | 0.79 | MAPK1 (0.58) | MAPK1LMNAALDH1A1HTTGAA | |
| SCHEMBL10860399 | 0.79 | MAPK1 (0.58) | MAPK1LMNAALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61291579-A | — | — | None | — | — | JP | disclosed |
| JP-S61291579-A | 1-(3-CINNAMYL)-4-ISOPROPYLCARBAMOYLPIPERAZINE AND PRODUCTION THEREOF | KYORIN PHARMACEUT CO LTD | 1986-12-22 | — | — | JP | disclosed |