Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587661 | 0.86 | NPC1 (0.54) | ALDH1A1GAAHTTMAPTKDM4E | |
| SCHEMBL7306504 | 0.84 | LMNA (0.58) | LMNAUSP2MEN1KMT2AALDH1A1 | |
| SCHEMBL10869289 | 0.82 | MAPK1 (0.73) | LMNAUSP2MEN1KMT2AALDH1A1 | |
| SCHEMBL9587878 | 0.82 | CYP3A4 (0.66) | LMNAUSP2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9587576 | 0.81 | MEN1 (0.57) | MEN1KMT2AGAAHTTCHRM3 | |
| SCHEMBL9587002 | 0.81 | KDM4E (0.61) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9598169 | 0.80 | HTT (0.64) | MEN1KMT2AALDH1A1GAAHTT | |
| SCHEMBL9587928 | 0.79 | CYP3A4 (0.53) | MEN1KMT2AGAAHTTKDM4E | |
| SCHEMBL9588899 | 0.78 | HSD17B10 (0.58) | GAAKDM4E | |
| SCHEMBL9589632 | 0.78 | HSD17B10 (0.58) | GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190974-A | Analgesics | ROUSSEL UCLAF (FR) | 1993-03-02 | — | — | US | disclosed |