Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29901003 | 0.83 | AMY1A (0.64) | KEAP1HSPA5CYP3A4HPGDMEN1 | |
| SCHEMBL30335116 | 0.82 | KEAP1 (0.75) | KEAP1BCL2BCL2L1ALOX5HSPA5 | |
| SCHEMBL87816 | 0.82 | KEAP1 (0.75) | KEAP1BCL2BCL2L1ALOX5HSPA5 | |
| SCHEMBL10869298 | 0.81 | ALOX5 (0.51) | KEAP1BCL2BCL2L1ALOX5IDH1 | |
| SCHEMBL27950266 | 0.80 | HSPA5 (0.58) | KEAP1BCL2BCL2L1ALOX5HSPA5 | |
| SCHEMBL27940865 | 0.80 | KEAP1 (0.72) | KEAP1BCL2BCL2L1ALOX5HSPA5 | |
| SCHEMBL27514066 | 0.80 | KEAP1 (0.72) | KEAP1BCL2BCL2L1ALOX5HSPA5 | |
| SCHEMBL28998999 | 0.80 | KEAP1 (0.72) | KEAP1BCL2BCL2L1ALOX5HSPA5 | |
| SCHEMBL27940823 | 0.80 | KEAP1 (0.72) | KEAP1BCL2BCL2L1ALOX5HSPA5 | |
| SCHEMBL27940839 | 0.80 | KEAP1 (0.72) | KEAP1BCL2BCL2L1ALOX5HSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186255-A2 | Process for preparing benzyl substituted phenols, dibenzylphenolic compounds, and the antioxidant use of such phenols | ETHYL CORPORATION (US) | 1986-07-02 | — | — | EP | disclosed |