Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.30 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380115 | 0.74 | TSHR (0.38) | CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL13993901 | 0.74 | GAA (0.32) | CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL269386 | 0.73 | — | — | |
| SCHEMBL14702913 | 0.72 | ALDH1A1 (0.36) | CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL6050270 | 0.72 | CYP1A2 (0.31) | CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL10605965 | 0.72 | TSHR (0.36) | CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL3982894 | 0.72 | CYP1A2 (0.31) | CYP1A2CYP2D6CYP2C19TDP1ALDH1A1 | |
| SCHEMBL4202415 | 0.70 | — | — | |
| SCHEMBL16975855 | 0.70 | OPRM1 (0.35) | OPRM1DRD3DRD2CYP1A2TDP1 | |
| Hydrochloric Acid SCHEMBL9514546 | 0.70 | KDM4E (0.30) | CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608308-B1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2021-07-21 | — | — | EP | disclosed |
| EP-0176049-A2 | Aminoalkylnaphtalene derivatives having pharmacological activities | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1986-04-02 | — | — | EP | disclosed |