SCHEMBL14702913

SCHEMBL14702913

CN(C)CC(C)(C)C(=O)Cl

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10602585 0.97 ALDH1A1 (0.35) ALDH1A1TSHRCYP1A2CYP2D6CYP2C19
SCHEMBL13695988 0.77 ALDH1A1 (0.35) ALDH1A1TSHRCYP1A2CYP2D6CYP2C19
SCHEMBL13993901 0.76 GAA (0.32) CYP1A2CYP2D6CYP2C19
SCHEMBL3380115 0.76 TSHR (0.38) ALDH1A1TSHRCYP1A2CYP2D6CYP2C19
Hydrochloric Acid SCHEMBL10605965 0.74 TSHR (0.36) ALDH1A1TSHRCYP1A2CYP2D6CYP2C19
SCHEMBL3982894 0.74 CYP1A2 (0.31) ALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL6050270 0.74 CYP1A2 (0.31) CYP1A2CYP2D6CYP2C19
SCHEMBL10869723 0.72 OPRM1 (0.36) ALDH1A1CYP1A2CYP2D6CYP2C19
Hydrochloric Acid SCHEMBL9514546 0.72 KDM4E (0.30) CYP1A2CYP2D6CYP2C19
Hydrochloric Acid SCHEMBL9514899 0.72 CYP1A2 (0.30) CYP1A2CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060926-A1 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME SAIL BIOMEDICINES INC (US) 2026-03-05 US disclosed
US-20250282749-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. 2025-09-11 US disclosed
EP-4581012-A2 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME Sail Biomedicines, Inc. (US) 2025-07-09 EP disclosed
EP-4469445-A1 COMPOUNDS AND METHODS OF USE Tango Therapeutics, Inc. (US) 2024-12-04 EP disclosed
WO-2024049979-A2 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME SENDA BIOSCIENCES, INC. (US) 2024-03-07 WO disclosed
WO-2023146991-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. (US) 2023-08-03 WO disclosed
WO-2023146991-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. (US) 2023-08-03 WO disclosed
US-20130040914-A1 PRODRUGS OF AN HIV REVERSE TRANSCRIPTASE INHIBITOR MERCK SHARP & DOHME CORP. 2013-02-14 US disclosed
US-20130040914-A1 PRODRUGS OF AN HIV REVERSE TRANSCRIPTASE INHIBITOR MERCK SHARP & DOHME CORP. 2013-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060926-A1 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME SGMS1, NPC1L1, SGMS2 ALDH1A1 2239/4885TSHR 379/4885CYP1A2 4683/4885
US-20250282749-A1 COMPOUNDS AND METHODS OF USE CYP1B1, CYP2C19, UGT1A1 ALDH1A1 193/4885TSHR 1531/4885CYP1A2 4/4885
US-20130040914-A1 PRODRUGS OF AN HIV REVERSE TRANSCRIPTASE INHIBITOR RNGTT, RPIA, REV1 ALDH1A1 477/4885TSHR 3872/4885CYP1A2 204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.