Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 8/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10869551 | 0.91 | PDE4A (0.48) | ALDH1A1POLBL3MBTL1KDM4EMAPT | |
| SCHEMBL10869823 | 0.90 | PDE4A (0.47) | ALDH1A1POLBL3MBTL1KDM4EMAPT | |
| SCHEMBL10870396 | 0.88 | PDE4A (0.50) | NPSR1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10869218 | 0.86 | ALDH1A1 (0.41) | NPSR1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10869472 | 0.82 | PDE4A (0.51) | ALDH1A1L3MBTL1KDM4EMAPTMAPK1 | |
| SCHEMBL10871167 | 0.81 | CYP1A2 (0.49) | NPSR1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10869230 | 0.81 | L3MBTL1 (0.47) | ALDH1A1POLBL3MBTL1KDM4EMAPT | |
| SCHEMBL10869629 | 0.80 | ALDH1A1 (0.39) | NPSR1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10869809 | 0.78 | PDE4A (0.49) | NPSR1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10870512 | 0.76 | PDE4A (0.47) | ALDH1A1L3MBTL1KDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185259-A2 | Pteridines, process for their preparation, and their use as intermediates or as medicaments | Dr. Karl Thomae GmbH (DE) | 1986-06-25 | — | — | EP | disclosed |