Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10869551 | 0.99 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL10869230 | 0.91 | L3MBTL1 (0.47) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL10869738 | 0.90 | NPSR1 (0.44) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL10870396 | 0.90 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL10869218 | 0.88 | ALDH1A1 (0.41) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL10870512 | 0.83 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL10870595 | 0.81 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL10869926 | 0.79 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL10870587 | 0.77 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL10868979 | 0.76 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185259-A2 | Pteridines, process for their preparation, and their use as intermediates or as medicaments | Dr. Karl Thomae GmbH (DE) | 1986-06-25 | — | — | EP | disclosed |