Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10872305 | 0.89 | MTNR1A (0.50) | HTR2AHTR1AMTNR1AMTNR1BMEN1 | |
| Bromide SCHEMBL10872043 | 0.89 | HTR7 (0.48) | HTR2AALDH1A1CYP2D6KDM4EMEN1 | |
| SCHEMBL10869866 | 0.86 | HTR2A (0.51) | HTR2AHTR1AALDH1A1MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL10870609 | 0.85 | HTR2A (0.50) | HTR2AHTR1AALDH1A1MEN1CYP1A2 | |
| SCHEMBL10866988 | 0.82 | HTR2A (0.59) | HTR2AHTR1AMTNR1AALDH1A1MTNR1B | |
| SCHEMBL10867787 | 0.77 | HTR2A (0.66) | HTR2AHTR1AMTNR1AALDH1A1MTNR1B | |
| SCHEMBL10873091 | 0.77 | SMN1; SMN2 (0.49) | HTR2AHTR1AALDH1A1CYP2D6KDM4E | |
| SCHEMBL24723815 | 0.76 | HTR2A (0.97) | HTR2AHTR1ACYP2D6MPOCYP1A2 | |
| SCHEMBL29633130 | 0.76 | HTR2A (0.97) | HTR2AHTR1ACYP2D6MPOCYP1A2 | |
| SCHEMBL25249411 | 0.76 | HTR2A (1.00) | HTR2AHTR1ACYP2D6MPOCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187619-A2 | 1,3-Disubstituted tetrahydropyridines | CIBA-GEIGY AG (CH) | 1986-07-16 | — | — | EP | claimed |
| EP-0187619-A2 | 1,3-Disubstituted tetrahydropyridines | CIBA-GEIGY AG (CH) | 1986-07-16 | — | — | EP | disclosed |