Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15291319 | 0.72 | JAK2 (0.39) | JAK2BRPF1NOS2 | |
| SCHEMBL8705808 | 0.70 | NOS2 (0.34) | JAK2NOS2 | |
| SCHEMBL9484204 | 0.69 | MAPT (0.33) | JAK2HTR2BNOS2 | |
| SCHEMBL28628275 | 0.69 | MAPT (0.33) | JAK2HTR2BNOS2 | |
| SCHEMBL3692772 | 0.69 | NOS2 (0.41) | JAK2BRPF1NOS2 | |
| SCHEMBL30785015 | 0.69 | NOS2 (0.41) | JAK2BRPF1NOS2 | |
| SCHEMBL3692774 | 0.69 | NOS2 (0.41) | JAK2BRPF1NOS2 | |
| SCHEMBL18830891 | 0.67 | JAK2 (0.36) | JAK2BRPF1NOS2 | |
| SCHEMBL28129799 | 0.66 | MAOB (0.43) | JAK2LMNA | |
| SCHEMBL29556997 | 0.65 | JAK2 (0.36) | JAK2LMNANOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185538-A2 | The synthesis of indole alkaloids | Kong, Yun Cheung, Dr. (HK) | 1986-06-25 | — | — | EP | disclosed |