Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692774 | 1.00 | NOS2 (0.41) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL3692772 | 1.00 | NOS2 (0.41) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL15291319 | 0.79 | JAK2 (0.39) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL28129799 | 0.76 | MAOB (0.43) | HSD17B10JAK2ALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL29556997 | 0.75 | JAK2 (0.36) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL8705808 | 0.73 | NOS2 (0.34) | NOS2ALOX15HSD17B10JAK2 | |
| SCHEMBL18830891 | 0.73 | JAK2 (0.36) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL30955850 | 0.72 | MAPT (0.35) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL16426791 | 0.71 | IKBKB (0.54) | JAK2GAANPSR1KDM4EALDH1A1 | |
| SCHEMBL16426716 | 0.71 | MAOB (0.48) | CYP19A1CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025093059-A1 | 3-(AMINO)METHYLENE INDOLINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | 徐诺药业(南京)有限公司 | 2025-05-08 | — | — | WO | claimed |
| CN-117624179-A | 3- (amino) methylene indoline derivative and preparation method and application thereof | 徐诺药业(南京)有限公司 | 2024-03-01 | — | — | CN | claimed |
| WO-2025093059-A1 | 3-(AMINO)METHYLENE INDOLINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | 徐诺药业(南京)有限公司 | 2025-05-08 | — | — | WO | disclosed |
| WO-2025093059-A1 | 3-(AMINO)METHYLENE INDOLINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | 徐诺药业(南京)有限公司 | 2025-05-08 | — | — | WO | disclosed |
| WO-2025093059-A1 | 3-(AMINO)METHYLENE INDOLINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | 徐诺药业(南京)有限公司 | 2025-05-08 | — | — | WO | disclosed |
| CN-117624179-A | 3- (amino) methylene indoline derivative and preparation method and application thereof | 徐诺药业(南京)有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117624179-A | 3- (amino) methylene indoline derivative and preparation method and application thereof | 徐诺药业(南京)有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117624179-A | 3- (amino) methylene indoline derivative and preparation method and application thereof | 徐诺药业(南京)有限公司 | 2024-03-01 | — | — | CN | disclosed |