Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | SNCA | P37840 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28628275 | 1.00 | MAPT (0.33) | MAPTMEN1KMT2AJAK2CA12 | |
| SCHEMBL7019655 | 0.80 | CA12 (0.37) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL30955850 | 0.79 | MAPT (0.35) | MAPTMEN1KMT2AJAK2CA12 | |
| SCHEMBL30603084 | 0.72 | MAPT (0.53) | MAPTCA12 | |
| SCHEMBL10871376 | 0.69 | JAK2 (0.33) | JAK2HTR2BNOS2 | |
| SCHEMBL30785015 | 0.69 | NOS2 (0.41) | JAK2CA12CA1CA2CA9 | |
| SCHEMBL15291319 | 0.69 | JAK2 (0.39) | MEN1KMT2AJAK2CA12CA1 | |
| SCHEMBL3692774 | 0.69 | NOS2 (0.41) | JAK2CA12CA1CA2CA9 | |
| SCHEMBL3692772 | 0.69 | NOS2 (0.41) | JAK2CA12CA1CA2CA9 | |
| SCHEMBL7591081 | 0.68 | MAPT (0.57) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5272143-A | 6-oxoazepinoindole compounds, and pharmaceutical compositions containing them | KALI-CHEMIE PHARMA GMBH (DE) | 1993-12-21 | — | — | US | disclosed |