Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791838 | 0.86 | GPR35 (0.54) | SMN1; SMN2LMNAMAPTGPR35NPSR1 | |
| SCHEMBL4326710 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTHTTGAAHDAC3 | |
| SCHEMBL6354542 | 0.81 | MAPT (0.56) | SMN1; SMN2MAPTNPSR1HTTGAA | |
| SCHEMBL4970698 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTHTTGAACYP1A2 | |
| SCHEMBL9445618 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAMAPTGPR35NPSR1 | |
| SCHEMBL13997712 | 0.74 | HDAC1 (0.42) | SMN1; SMN2LMNAMAPTGPR35POLB | |
| SCHEMBL9505815 | 0.73 | POLB (0.55) | SMN1; SMN2LMNAMAPTNPSR1POLB | |
| SCHEMBL9360691 | 0.73 | PDPK1 (0.56) | SMN1; SMN2MAPTGPR35POLBGAA | |
| SCHEMBL915213 | 0.72 | MEN1 (0.64) | SMN1; SMN2LMNAMAPTGPR35POLB | |
| SCHEMBL427418 | 0.72 | HTT (0.67) | SMN1; SMN2LMNAMAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4602961-A | MONOAZO BENZOTHIAZOLE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1986-07-29 | — | — | US | disclosed |