Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053641 | 0.89 | TTR (0.53) | TTRALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL7058048 | 0.84 | KDM4E (0.52) | GPR84KDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL379864 | 0.80 | KDM4E (0.48) | GPR84KDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL8599050 | 0.77 | TTR (0.46) | TTRALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL10351393 | 0.77 | TYMS (0.44) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL30130196 | 0.77 | MEN1 (0.56) | TTRKDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL354514 | 0.77 | MEN1 (0.56) | TTRKDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL29364188 | 0.77 | MEN1 (0.56) | TTRKDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL16144676 | 0.75 | MEN1 (0.53) | KDM4EALDH1A1MAPTTDP1HPGD | |
| SCHEMBL29634145 | 0.75 | MEN1 (0.53) | KDM4EALDH1A1MAPTTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195743-A2 | Enol ethers, process for their preparation, alpha-pyrones, process for their preparation and use of the alpha-pyrones | CIBA-GEIGY AG (CH) | 1986-09-24 | — | — | EP | disclosed |