SCHEMBL8599050

SCHEMBL8599050

O=C(O)Oc1cc2c(cc1Cl)C(=O)c1ccccc1C2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 3/20 0.46
BCL2 P10415 1/20 0.44
MCL1 Q07820 1/20 0.44
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
MAPT P10636 4/20 0.41
TDP1 Q9NUW8 3/20 0.41
POLB P06746 2/20 0.41
PTPRC P08575 3/20 0.41
S100A4 P26447 1/20 0.41
CDC25B P30305 1/20 0.40
ACE2 Q9BYF1 1/20 0.40
IDO1 P14902 1/20 0.39
DNMT1 P26358 1/20 0.39
DNMT3L Q9UJW3 1/20 0.39
DNMT3A Q9Y6K1 1/20 0.39
FABP7 O15540 1/20 0.38
FABP3 P05413 1/20 0.38
FABP5 Q01469 1/20 0.38
ALDH1A1 P00352 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6053641 0.88 TTR (0.53) TTRBCL2MCL1MEN1KMT2A
SCHEMBL10873019 0.77 TTR (0.42) TTRBCL2MCL1MEN1KMT2A
SCHEMBL2125571 0.75 MEN1 (0.63) TTRBCL2MCL1MEN1KMT2A
SCHEMBL29651770 0.75 MEN1 (0.63) TTRBCL2MCL1MEN1KMT2A
SCHEMBL9173826 0.75 S100A4 (0.42) TTRBCL2MCL1MEN1KMT2A
SCHEMBL5308077 0.74 BCL2 (0.58) BCL2MCL1MEN1KMT2AMAPT
SCHEMBL8769865 0.74 MAPT (0.49) TTRBCL2MCL1MEN1KMT2A
SCHEMBL9509350 0.74 CYP1A1 (0.56) TTRMCL1MEN1KMT2AMAPT
SCHEMBL7055073 0.74 TTR (0.55) TTRBCL2MCL1MEN1KMT2A
SCHEMBL3912083 0.74 TTR (0.55) TTRBCL2MCL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0591000-B1 Finely divided anthraquinone formulations as inhibitors of sulfide production from sulfate-reducing bacteria BIO TECH RESOURCES (US) 1998-04-15 EP claimed
EP-0525073-B1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA DU PONT (US) 1994-05-25 EP claimed