Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | AR | P10275 | 6/20 | 0.42 |
| ▸ | PGR | P06401 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SHBG | P04278 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10872314 | 0.94 | PGR (0.44) | LMNAMAPTARPGRKMT2A | |
| SCHEMBL10873501 | 0.89 | PGR (0.49) | LMNAMAPTARPGRKMT2A | |
| SCHEMBL11856995 | 0.87 | LMNA (0.57) | LMNAMAPTARPGRKMT2A | |
| SCHEMBL10874229 | 0.80 | PGR (0.56) | LMNAARPGRKMT2AMEN1 | |
| SCHEMBL10881901 | 0.78 | PGR (0.47) | LMNAMAPTARPGRKMT2A | |
| SCHEMBL25863267 | 0.78 | PGR (0.63) | LMNAMAPTARPGRKMT2A | |
| SCHEMBL11694580 | 0.78 | PGR (0.63) | LMNAMAPTARPGRKMT2A | |
| SCHEMBL25863270 | 0.78 | PGR (0.63) | LMNAMAPTARPGRKMT2A | |
| SCHEMBL25863273 | 0.78 | PGR (0.63) | LMNAMAPTARPGRKMT2A | |
| SCHEMBL25863269 | 0.78 | PGR (0.63) | LMNAMAPTARPGRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092173-B1 | 11-BETA-CHLOROSTEROIDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-03-05 | — | — | EP | claimed |