Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UMPS | P11172 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 3/20 | 0.36 |
| ▸ | PYGM | P11217 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873399 | 1.00 | UMPS (0.39) | UMPSPNPMAPTSMN1; SMN2MEN1 | |
| SCHEMBL29286002 | 0.82 | UMPS (0.42) | UMPSPNPLMNAGBA1PYGL | |
| SCHEMBL31565646 | 0.82 | PYGM (0.41) | UMPSPNPLMNAGBA1PYGL | |
| SCHEMBL29510865 | 0.81 | UMPS (0.39) | UMPSPNPPYGLPYGMB4GALT1 | |
| SCHEMBL30751087 | 0.81 | SLC5A2 (0.40) | UMPSPYGLPYGM | |
| SCHEMBL29423327 | 0.81 | UMPS (0.39) | UMPSPNPPYGLPYGMB4GALT1 | |
| SCHEMBL31357478 | 0.80 | UMPS (0.38) | UMPSPNPMAPTSMN1; SMN2LMNA | |
| SCHEMBL30295613 | 0.77 | TK2 (0.45) | UMPSPNPMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8995414 | 0.77 | UMPS (0.36) | UMPSPNPLMNAPYGLTSHR | |
| SCHEMBL30295619 | 0.77 | TK2 (0.45) | UMPSPNPMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204264-A2 | Conversion of uracil derivatives to cytosine derivatives | Takeda Chemical Industries, Ltd. (JP) | 1986-12-10 | — | — | EP | disclosed |