Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UMPS | P11172 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 3/20 | 0.35 |
| ▸ | PNP | P00491 | 3/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | IL6 | P05231 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751087 | 0.79 | SLC5A2 (0.40) | UMPSPYGLSLC5A2 | |
| SCHEMBL29286002 | 0.77 | UMPS (0.42) | UMPSPYGLPNPLMNA | |
| SCHEMBL10873399 | 0.77 | UMPS (0.39) | UMPSPYGLPNPLMNATSHR | |
| SCHEMBL31565646 | 0.77 | PYGM (0.41) | UMPSPYGLPNPLMNA | |
| SCHEMBL10873403 | 0.77 | UMPS (0.39) | UMPSPYGLPNPLMNATSHR | |
| SCHEMBL29510865 | 0.76 | UMPS (0.39) | UMPSPYGLPNPSLC5A2 | |
| SCHEMBL29423327 | 0.76 | UMPS (0.39) | UMPSPYGLPNPSLC5A2 | |
| SCHEMBL31357478 | 0.75 | UMPS (0.38) | UMPSPYGLPNPLMNATSHR | |
| SCHEMBL30295619 | 0.72 | TK2 (0.45) | UMPSPYGLPNPTSHR | |
| SCHEMBL30295613 | 0.72 | TK2 (0.45) | UMPSPYGLPNPTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726904-A1 | 5-FLUOROURACIL DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012606-A1 | 5-FLUOROURACIL DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-05-11 | — | — | WO | disclosed |