Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10756839 | 0.90 | KDM4E (0.40) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10923661 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10875722 | 0.86 | ALDH1A1 (0.47) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10874188 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL6240583 | 0.83 | ALDH1A1 (0.47) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10929947 | 0.83 | KDM4E (0.39) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10863231 | 0.82 | POLB (0.41) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10875591 | 0.82 | PIK3CD (0.40) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL11114605 | 0.81 | PIK3CG (0.42) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9416420 | 0.81 | PIK3CD (0.42) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203488-A2 | 7-Azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinoline carboxylic acids and 1,8-naphthyridine carboxylic acids, process for their preparation and bactericidal agents containing them | BAYER AG (DE) | 1986-12-03 | — | — | EP | disclosed |