Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TOP2A | P11388 | 3/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217185 | 0.90 | KDM4E (0.50) | ALDH1A1KDM4ELMNATOP2ATOP2B | |
| SCHEMBL10923486 | 0.86 | KDM4E (0.47) | ALDH1A1KDM4ELMNATOP2ATOP2B | |
| SCHEMBL6240583 | 0.86 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNATOP2ATOP2B | |
| SCHEMBL10874196 | 0.86 | KDM4E (0.38) | ALDH1A1KDM4ELMNATOP2ATOP2B | |
| SCHEMBL10875970 | 0.84 | KDM4E (0.64) | ALDH1A1KDM4ELMNATOP2ATOP2B | |
| SCHEMBL10590990 | 0.84 | KDM4E (0.42) | ALDH1A1KDM4ELMNATOP2ATOP2B | |
| SCHEMBL9665896 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNATOP2ATOP2B | |
| SCHEMBL10875591 | 0.82 | PIK3CD (0.40) | ALDH1A1KDM4ELMNATOP2ATOP2B | |
| SCHEMBL10591014 | 0.82 | KDM4E (0.44) | ALDH1A1KDM4ELMNATOP2ATOP2B | |
| SCHEMBL9370629 | 0.82 | KDM4E (0.61) | ALDH1A1KDM4ELMNATOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203488-A2 | 7-Azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinoline carboxylic acids and 1,8-naphthyridine carboxylic acids, process for their preparation and bactericidal agents containing them | BAYER AG (DE) | 1986-12-03 | — | — | EP | disclosed |