SCHEMBL1087463

SCHEMBL1087463

CC(C)C(OC(=O)C=Cc1ccccc1)C(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B10 O60218 2/20 0.56
AKR1B1 P15121 2/20 0.56
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
CA14 Q9ULX7 1/20 0.56
TDP1 Q9NUW8 2/20 0.53
GLA P06280 1/20 0.53
KMT2A Q03164 3/20 0.52
MEN1 O00255 1/20 0.52
LMNA P02545 4/20 0.52
MAPT P10636 3/20 0.52
ALDH1A1 P00352 2/20 0.52
HCAR2 Q8TDS4 2/20 0.52
HDAC3 O15379 2/20 0.52
HDAC4 P56524 2/20 0.52
HDAC1 Q13547 2/20 0.52
HDAC2 Q92769 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1087461 1.00 AKR1B10 (0.56) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL23702413 0.88 AKR1B10 (0.54) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL23702414 0.88 AKR1B10 (0.54) AKR1B10AKR1B1CA12CA1CA2
Isopropyl Cinnamate SCHEMBL133105 0.87 AKR1B10 (0.72) AKR1B10AKR1B1CA12CA1CA2
Isopropyl Cinnamate SCHEMBL133104 0.87 AKR1B10 (0.72) AKR1B10AKR1B1CA12CA1CA2
Isopropyl Cinnamate SCHEMBL11996898 0.87 AKR1B10 (0.72) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL14960686 0.87 AKR1B10 (0.57) AKR1B10AKR1B1CA12CA1CA2
Isopropyl Cinnamate SCHEMBL28009788 0.86 AKR1B10 (0.70) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL8854386 0.86 AKR1B10 (0.56) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL8854383 0.86 AKR1B10 (0.56) AKR1B10AKR1B1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2575750-A2 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE International Flora Technologies, Ltd. (US) 2013-04-10 EP claimed
US-8152860-B2 Cosmetic composition for coloring hair comprising a direct hair dye and a carrier system comprising polysaccharides ROVI COSMETICS INTERNATIONAL GMBH (DE) 2012-04-10 US claimed
WO-2011149929-A2 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-12-01 WO claimed
US-20110286946-A1 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-11-24 US claimed
US-20110200666-A1 UV PROTECTION AGENT FOR THE SKIN OR HAIR HAVING A UV FILTER SUBSTANCE ENCAPSULATED IN A VESICULAR CARRIER SYSTEMü ROVI COSMETICS INTERNATIONAL GMBH (DE) 2011-08-18 US claimed
CN-120076778-A Method for providing high SPF to a local surface of a body 联合利华知识产权控股有限公司 2025-05-30 CN disclosed
CN-113616540-B Novel occlusive formulations 株式会社LG生活健康 2023-11-03 CN disclosed
CN-116472023-A Deuterated polyunsaturated fatty acids or esters thereof for cosmetic applications 拜奥吉瓦有限责任公司 2023-07-21 CN disclosed
CN-115551471-A Cosmetic compositions and methods comprising Plumeria rubra extract 玫琳凯有限公司 2022-12-30 CN disclosed
CN-115087427-A Herbal cosmetic composition for treating skin 玫琳凯有限公司 2022-09-20 CN disclosed
CN-113616540-A Novel occlusive formulations 株式会社LG生活健康 2021-11-09 CN disclosed
CN-108472226-B Novel occlusive formulations 株式会社LG生活健康 2021-11-05 CN disclosed
CN-105916835-B Hydroxytyrosol derivatives, their preparation and use in personal care 伊士曼化工公司 2021-07-16 CN disclosed
CN-111801108-A Topical skin care compositions 斯金基克有限责任公司 2020-10-20 CN disclosed
CN-105073085-B Active agent combination comprising at least one essential oil, one cyclodextrin and one liquid fatty substance, and composition comprising same 欧莱雅 2020-02-21 CN disclosed
EP-2575750-A2 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE International Flora Technologies, Ltd. (US) 2013-04-10 EP disclosed
US-8152860-B2 Cosmetic composition for coloring hair comprising a direct hair dye and a carrier system comprising polysaccharides ROVI COSMETICS INTERNATIONAL GMBH (DE) 2012-04-10 US disclosed
WO-2011149929-A2 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-12-01 WO disclosed
US-20110286946-A1 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-11-24 US disclosed
US-20110200666-A1 UV PROTECTION AGENT FOR THE SKIN OR HAIR HAVING A UV FILTER SUBSTANCE ENCAPSULATED IN A VESICULAR CARRIER SYSTEMü ROVI COSMETICS INTERNATIONAL GMBH (DE) 2011-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110200666-A1 UV PROTECTION AGENT FOR THE SKIN OR HAIR HAVING A UV FILTER SUBSTANCE ENCAPSULATED IN A VESICULAR CARRIER SYSTEMü HNRNPU, CD44, CUTA AKR1B10 3974/4885AKR1B1 4598/4885CA12 1023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.