Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.43 |
| ▸ | WNT3A | P56704 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10877130 | 0.84 | SRD5A2 (0.49) | MEN1KMT2AHPGDSRD5A2ALDH1A1 | |
| SCHEMBL10878497 | 0.80 | SRD5A2 (0.52) | MEN1KMT2AHPGDSRD5A2ALDH1A1 | |
| SCHEMBL10876017 | 0.78 | TSHR (0.54) | ALDH1A1MAPK1GAAMAPTCTNNB1 | |
| SCHEMBL10877366 | 0.76 | PDE3B (0.49) | MEN1KMT2AHPGDALDH1A1RAB9A | |
| SCHEMBL10879697 | 0.76 | PDE3B (0.49) | HPGDALDH1A1MAPK1KDM4ETSHR | |
| SCHEMBL10878768 | 0.74 | HPGD (0.47) | MEN1KMT2AHPGDALDH1A1RAB9A | |
| SCHEMBL10876292 | 0.73 | PDE3B (0.72) | KMT2AHPGDTSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL10921324 | 0.73 | ALDH1A1 (0.46) | ALDH1A1RAB9ANPC1MAPK1KDM4E | |
| SCHEMBL5469811 | 0.72 | MEN1 (0.70) | MEN1KMT2AHPGDALDH1A1RAB9A | |
| SCHEMBL4824941 | 0.71 | SRD5A2 (0.82) | MEN1KMT2AHPGDSRD5A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065165-B1 | 5-OXYMETHYL-4-ACYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-06-18 | — | — | EP | disclosed |
| US-4526981-A | [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0065165-A1 | 5-Oxymethyl-4-acyl-1,3-dihydro-2H-imidazol-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-24 | — | — | EP | disclosed |