Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 5/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL1410762 | 0.97 | MAPT (0.56) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| Bisphenol A SCHEMBL7055236 | 0.97 | MAPT (0.56) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL4859006 | 0.97 | MAPT (0.55) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL9246472 | 0.93 | MAPT (0.60) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| Bisphenol A SCHEMBL6678074 | 0.93 | KMT2A (0.50) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| Bicarbonate SCHEMBL9249849 | 0.92 | MAPT (0.58) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL10875111 | 0.92 | MAPT (0.56) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| Bisphenol A SCHEMBL7535174 | 0.90 | KMT2A (0.50) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL2854092 | 0.89 | MAPT (0.56) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL17889901 | 0.88 | MAPT (0.51) | MAPTTDP1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132588-A1 | A POLYCARBONATE COMPOSITION WITH IMPROVED FLAME PROPERTIES | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2024-06-27 | — | — | WO | disclosed |
| EP-4389824-A1 | A POLYCARBONATE COMPOSITION WITH IMPROVED FLAME PROPERTIES | SABIC Global Technologies B.V. (NL) | 2024-06-26 | — | — | EP | disclosed |
| EP-4286479-A1 | THERMOPLASTIC COMPOSITIONS HAVING HIGH METAL BONDING FORCE FOR NMT APPLICATIONS | SHPP Global Technologies B.V. (NL) | 2023-12-06 | — | — | EP | disclosed |
| EP-4209552-A1 | ARTICLES AND STRUCTURES OF WAVE ABSORPTION MATERIAL | SHPP Global Technologies B.V. (NL) | 2023-07-12 | — | — | EP | disclosed |
| EP-4209551-A1 | THERMOPLASTIC COMPOSITIONS WITH IMPROVED PERFORMANCE FOR NANO MOLDING TECHNOLOGY (NMT) | SHPP Global Technologies B.V. (NL) | 2023-07-12 | — | — | EP | disclosed |
| EP-2888324-B1 | IMPROVED POLYCARBONATE COMPOSITIONS | SHPP GLOBAL TECH BV (NL) | 2023-06-14 | — | — | EP | disclosed |
| EP-4183812-A1 | THERMOPLASTIC COMPOSITIONS HAVING IMPROVED TRANSMISSION AND HAZE PROPERTIES | SHPP Global Technologies B.V. (NL) | 2023-05-24 | — | — | EP | disclosed |
| EP-4183825-A1 | THERMOPLASTIC FILM COMPOSITIONS HAVING IMPROVED BLUE LED LIGHT STABILITY | SHPP Global Technologies B.V. (NL) | 2023-05-24 | — | — | EP | disclosed |
| US-20220220312-A1 | THERMOPLASTIC COMPOSITIONS, METHODS OF THEIR MANUFACTURE, AND ARTICLES THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2022-07-14 | — | — | US | disclosed |
| US-20220135790-A1 | COMPOSITIONS HAVING IMPROVED CHEMICAL RESISTANCE, ARTICLES FORMED THEREOF, AND METHODS OF MANUFACTURE | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2022-05-05 | — | — | US | disclosed |
| US-20070155913-A1 | Thermoplastic composition, method of making, and articles formed therefrom | CITIBANK, N.A., AS COLLATERAL AGENT | 2007-07-05 | — | — | US | disclosed |
| US-20070129492-A1 | POLYSILOXANE COPOLYMERS, THERMOPLASTIC COMPOSITION, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2007-06-07 | — | — | US | disclosed |
| WO-2007061672-A2 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |
| US-20070117957-A1 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2007-05-24 | — | — | US | disclosed |
| WO-2007053500-A1 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2007-05-10 | — | — | WO | disclosed |
| US-20070100059-A1 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2007-05-03 | — | — | US | disclosed |
| EP-1423995-B1 | SHEET MATERIAL AND ITS USE IN CIRCUIT BOARDS | DU PONT (US) | 2006-10-04 | — | — | EP | disclosed |
| US-6929848-B2 | Sheet material especially useful for circuit boards | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2005-08-16 | — | — | US | disclosed |
| US-20050136233-A1 | Sheet material especially useful for circuit boards | SAMUELS MICHAEL R (US) | 2005-06-23 | — | — | US | disclosed |
| US-20030087077-A1 | Sheet material especially useful for circuit boards | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-05-08 | — | — | US | disclosed |