Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 2/20 | 0.41 |
| ▸ | FPR1 | P21462 | 2/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10676698 | 0.76 | REN (0.51) | MAOAKDM1AMAOBRENFPR1 | |
| SCHEMBL10675560 | 0.76 | REN (0.51) | MAOAKDM1AMAOBRENFPR1 | |
| SCHEMBL10675547 | 0.76 | REN (0.51) | MAOAKDM1AMAOBRENFPR1 | |
| SCHEMBL10676707 | 0.76 | REN (0.51) | MAOAKDM1AMAOBRENFPR1 | |
| SCHEMBL10675553 | 0.76 | REN (0.51) | MAOAKDM1AMAOBRENFPR1 | |
| Hydrochloric Acid SCHEMBL10680208 | 0.74 | REN (0.50) | MAOAKDM1AMAOBRENFPR1 | |
| SCHEMBL9148331 | 0.73 | KDM1A (0.53) | GID4MAOAKDM1AMAOBCACNA1S | |
| SCHEMBL9145505 | 0.73 | KDM1A (0.53) | GID4MAOAKDM1AMAOBCACNA1S | |
| SCHEMBL27569651 | 0.72 | EDNRA (0.52) | GID4MAOAKDM1AMAOBCACNA1S | |
| SCHEMBL10724458 | 0.71 | MAOA (0.43) | GID4MAOAKDM1AMAOBREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201085-A2 | 6-Phenyl-1,2,3,4,4a,5,6,10b-octahydrobenz(h) isoquinolines | PENNWALT CORPORATION (US) | 1986-11-12 | — | — | EP | disclosed |