Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28488567 | 1.00 | ATM (0.56) | ATMALDH1A1NAAATSHRHPGD | |
| SCHEMBL1759156 | 0.94 | ATM (0.50) | ATMALDH1A1NAAATSHRHPGD | |
| SCHEMBL1759154 | 0.94 | ATM (0.50) | ATMALDH1A1NAAATSHRHPGD | |
| SCHEMBL1759155 | 0.94 | ATM (0.50) | ATMALDH1A1NAAATSHRHPGD | |
| SCHEMBL12803598 | 0.92 | FAAH (0.51) | ATMALDH1A1NAAATSHRHPGD | |
| SCHEMBL12803688 | 0.92 | ATM (0.48) | ATMALDH1A1NAAATSHRHPGD | |
| SCHEMBL12803685 | 0.92 | ATM (0.48) | ATMALDH1A1NAAATSHRHPGD | |
| SCHEMBL12803597 | 0.92 | FAAH (0.51) | ATMALDH1A1NAAATSHRHPGD | |
| SCHEMBL6345681 | 0.91 | NAAA (0.67) | ATMNAAATSHRHCAR2DGKA | |
| SCHEMBL6344659 | 0.91 | NAAA (0.67) | ATMNAAATSHRHCAR2DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4575562-A | CARBONYLATION, ESTERIFICATION, QUINONE OXIDANT, HYDROGENATION | MONSANTO COMPANY (US) | 1986-03-11 | — | — | US | disclosed |