Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11040780 | 0.99 | NPC1 (0.60) | NPC1ALDH1A1KDM4ECYP1A2RAB9A | |
| SCHEMBL10881018 | 0.91 | SMN1; SMN2 (0.58) | NPC1ALDH1A1KDM4ECYP1A2RAB9A | |
| Hydrochloric Acid SCHEMBL10878734 | 0.87 | SMN1; SMN2 (0.54) | NPC1ALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL10880785 | 0.86 | RAB9A (0.64) | NPC1ALDH1A1KDM4ECYP1A2RAB9A | |
| SCHEMBL10880685 | 0.86 | NPC1 (0.64) | NPC1ALDH1A1KDM4ECYP1A2RAB9A | |
| Hydrochloric Acid SCHEMBL10876746 | 0.85 | NPC1 (0.63) | NPC1ALDH1A1KDM4ECYP1A2RAB9A | |
| SCHEMBL10878024 | 0.85 | MAPT (0.51) | NPC1ALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL8770633 | 0.78 | NPC1 (0.80) | NPC1ALDH1A1KDM4ECYP1A2RAB9A | |
| SCHEMBL10877468 | 0.77 | NR1H4 (0.55) | NPC1ALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL10880536 | 0.76 | NPC1 (0.78) | NPC1ALDH1A1KDM4ECYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0100051-B1 | NEW DERIVATIVES OF 1-ALKYLAMINE-(4(P-ALKYLOXY-BENZAMIDE)PHENOXY)-2-PROPANOL, HAVING BETA-SYMPATHOLYTIC ACTIVITY, THEIR SALTS, AND PRODUCTION PROCESSES THEREOF | A. Menarini S.a.S. (IT) | 1986-04-09 | — | — | EP | disclosed |