Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10878440 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9492368 | 0.88 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9492364 | 0.88 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9491356 | 0.86 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9491360 | 0.86 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9494852 | 0.84 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9494847 | 0.84 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9494802 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9494800 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL10721434 | 0.83 | LMNA (0.42) | ALDH1A1MEN1KMT2AGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4582841-A | ANTITUMOR AND -CARCINOGENIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0085275-B1 | SUBSTITUTED THIAZOLIDINYLIC ESTERS OF MINERAL ACIDS | CIBA-GEIGY AG (CH) | 1986-02-19 | — | — | EP | disclosed |
| US-4489069-A | ANTITUMOR | CIBA-GEIGY AG (CH) | 1984-12-18 | — | — | US | disclosed |
| EP-0085275-A1 | Substituted thiazolidinylic esters of mineral acids | CIBA-GEIGY AG (CH) | 1983-08-10 | — | — | EP | disclosed |