Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491356 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9494847 | 0.89 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9494852 | 0.89 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL10878445 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL10878440 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9492368 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9492364 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9494802 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9494800 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AGAATSHR | |
| Phosphoric Acid SCHEMBL10880246 | 0.81 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494047-A1 | Use of carbazones for the treatment of rheumatoid diseases | CIBA-GEIGY AG (CH) | 1992-07-08 | — | — | EP | claimed |
| US-5177091-A | Rheumatic disorders | CIBA-GEIGY CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0494047-A1 | Use of carbazones for the treatment of rheumatoid diseases | CIBA-GEIGY AG (CH) | 1992-07-08 | — | — | EP | disclosed |