SCHEMBL10878469

SCHEMBL10878469

CC(=O)COOCC(O)CO

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.38
KDM4E B2RXH2 2/20 0.38
DUSP3 P51452 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
USP2 O75604 1/20 0.34
ALDH1A1 P00352 1/20 0.33
DGKA P23743 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
CYP1A2 P05177 2/20 0.32
AGTR1 P30556 1/20 0.32
FAAH O00519 2/20 0.31
PLA2G2C Q5R387 1/20 0.30
AR P10275 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27310520 0.84 LMNA (0.41) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL17237690 0.82 LMNA (0.36) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL28810599 0.82 LMNA (0.36) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL27797847 0.80 USP2 (0.44) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL27828601 0.80 USP2 (0.44) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL516221 0.80 USP2 (0.44) LMNAKDM4EDUSP3MEN1KMT2A
Ethane SCHEMBL28093262 0.78 LMNA (0.47) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL30755 0.78 LMNA (0.53) LMNAKDM4EDUSP3MEN1KMT2A
Bicarbonate SCHEMBL29257272 0.77 USP2 (0.41) LMNAKDM4EDUSP3MEN1KMT2A
Propane SCHEMBL27657560 0.76 USP2 (0.46) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150321992-A1 TRIACYLGLYCEROL OLIGOMERS TRENT UNIVERSITY (CA) 2015-11-12 US disclosed
WO-2015168789-A1 TRIACYLGLYCEROL OLIGOMERS TRENT UNIVERSITY (CA) 2015-11-12 WO disclosed
EP-0080502-B1 ISOLATION OF PROTEIN AND PEPTIDE FROM URINE THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) 1986-01-29 EP disclosed
US-4359415-A Isolation of an antineoplastic protein fraction and an antineoplastic peptide fraction from human urine UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) 1982-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150321992-A1 TRIACYLGLYCEROL OLIGOMERS SQLE, DGAT2, PNLIP LMNA 1104/4885KDM4E 4878/4885DUSP3 4322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.