Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | EBP | Q15125 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10878610 | 0.94 | EBP (0.57) | SIGMAR1EBPKDM4EHRH3MEN1 | |
| SCHEMBL10794566 | 0.92 | FDPS (0.45) | SIGMAR1EBPKDM4EFDPSKMT2A | |
| SCHEMBL10878998 | 0.88 | EBP (0.63) | SIGMAR1EBPKDM4EHRH3FDPS | |
| SCHEMBL10893332 | 0.87 | EBP (0.41) | SIGMAR1EBPKDM4EMAOBMEN1 | |
| SCHEMBL10883714 | 0.86 | GALR3 (0.48) | SIGMAR1EBPKDM4EHRH3FDPS | |
| SCHEMBL10741572 | 0.86 | KDM4E (0.53) | SIGMAR1EBPKDM4EHRH3MEN1 | |
| SCHEMBL10795277 | 0.83 | LTA4H (0.44) | SIGMAR1EBPKDM4EMAOBESR1 | |
| SCHEMBL10878286 | 0.81 | EBP (0.72) | SIGMAR1EBPKDM4EHRH3FDPS | |
| SCHEMBL10880850 | 0.80 | HRH3 (0.48) | SIGMAR1EBPKDM4EHRH3FDPS | |
| SCHEMBL10877202 | 0.80 | EBP (0.49) | SIGMAR1EBPKDM4EHRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605672-A | ANTIDEPRESSANTS; TREATMENT OF ETHANOLIC INTOXICATION; LOW TOXICITY AND FEW SIDE EFFECTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1986-08-12 | — | — | US | claimed |
| EP-0115080-B1 | (OMEGA-(DIETHYLAMINO)-ALKOXY)-ALPHA-(ETHYL)-BENZHYDROL DERIVATIVES, THEIR ACID ADDITION SALTS AND QUATERNARY SALTS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-04-16 | — | — | EP | claimed |
| US-4605672-A | ANTIDEPRESSANTS; TREATMENT OF ETHANOLIC INTOXICATION; LOW TOXICITY AND FEW SIDE EFFECTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1986-08-12 | — | — | US | disclosed |