Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10828004 | 0.86 | KDM4E (0.64) | KDM4EALDH1A1LTA4HCACNA1BFAAH | |
| SCHEMBL10874866 | 0.85 | FFAR4 (0.50) | KDM4EALDH1A1LTA4HCACNA1BL3MBTL1 | |
| SCHEMBL465562 | 0.84 | LTA4H (0.59) | ALDH1A1LTA4HPPARGPPARAHDAC1 | |
| SCHEMBL10876432 | 0.83 | TDP1 (0.53) | KDM4EALDH1A1LTA4HALOX5PPARG | |
| SCHEMBL10878574 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1LTA4HFAAHPPARG | |
| SCHEMBL9162147 | 0.79 | PPARA (0.48) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL10877393 | 0.79 | LTA4H (0.56) | KDM4ELTA4HCACNA1BFAAHPPARA | |
| SCHEMBL11396009 | 0.79 | MAPK14 (0.47) | KDM4EALDH1A1LTA4HPPARGPPARA | |
| SCHEMBL10877752 | 0.77 | TSPO (0.46) | ALDH1A1LTA4HL3MBTL1SMN1; SMN2 | |
| SCHEMBL10878193 | 0.77 | PPARA (0.45) | KDM4EALDH1A1LTA4HPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4625048-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1986-11-25 | — | — | US | disclosed |