Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10878353 | 0.86 | MAPT (0.47) | ALDH1A1RAB9AHTTSMN1; SMN2GAA | |
| SCHEMBL10879067 | 0.86 | FAAH (0.46) | ALDH1A1SMN1; SMN2FAAHCYP1A2POLB | |
| SCHEMBL10877406 | 0.85 | FAAH (0.50) | ALDH1A1GAAKMT2AFAAHCYP1A2 | |
| SCHEMBL10881215 | 0.84 | FAAH (0.44) | ALDH1A1SMN1; SMN2KMT2AFAAHCYP1A2 | |
| SCHEMBL10877636 | 0.83 | ALDH1A1 (0.51) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL10881540 | 0.81 | FAAH (0.54) | FAAH | |
| SCHEMBL16907464 | 0.79 | MAPT (0.66) | ALDH1A1RAB9AHTTSMN1; SMN2GAA | |
| SCHEMBL28209722 | 0.79 | KMT2A (0.62) | ALDH1A1RAB9AHTTSMN1; SMN2GAA | |
| Flumecinol SCHEMBL667363 | 0.79 | ALDH1A1 (0.45) | ALDH1A1RAB9AHTTSMN1; SMN2KMT2A | |
| SCHEMBL10877722 | 0.79 | ALDH1A1 (0.50) | ALDH1A1RAB9AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564630-A | ANTILIPEMIC AGENTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1986-01-14 | — | — | US | claimed |
| EP-0116234-A1 | Carbamyloxybenzhydrole derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-22 | — | — | EP | claimed |
| EP-0116234-B1 | CARBAMYLOXYBENZHYDROLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1986-03-26 | — | — | EP | disclosed |
| US-4564630-A | ANTILIPEMIC AGENTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1986-01-14 | — | — | US | disclosed |
| EP-0116234-A1 | Carbamyloxybenzhydrole derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-22 | — | — | EP | disclosed |