Flumecinol

Flumecinol

SCHEMBL667363

CCC(O)(c1ccccc1)c1cccc(C(F)(F)F)c1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
TSHR P16473 2/20 0.45
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 1/20 0.44
KIF11 P52732 1/20 0.44
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
POLB P06746 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MAPT P10636 2/20 0.42
HTT P42858 1/20 0.42
RAB9A P51151 1/20 0.42
CES2 O00748 1/20 0.42
MGLL Q99685 1/20 0.42
MAPK1 P28482 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
HTR2B P41595 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10740804 0.88 ESR1 (0.47) ALDH1A1KIF11MEN1KMT2APOLB
SCHEMBL11623260 0.87 ALDH1A1 (0.56) ALDH1A1TSHRCYP3A4CYP2D6KIF11
SCHEMBL10783493 0.84 NR4A2 (0.55) POLBMAPTHTTL3MBTL1
SCHEMBL246639 0.82 SMN1; SMN2 (0.52) CYP3A4CYP2D6MEN1KMT2ACYP1A2
SCHEMBL10901479 0.81 NR4A2 (0.52) POLBMAPTHTTL3MBTL1
SCHEMBL936317 0.80 SMN1; SMN2 (0.50) ALDH1A1CYP3A4CYP2D6MEN1KMT2A
SCHEMBL28539349 0.80 CHRM2 (0.50) CYP3A4CYP2D6MEN1KMT2ACYP1A2
SCHEMBL7808926 0.80 KIF11 (0.47) ALDH1A1CYP3A4KIF11SMN1; SMN2LMNA
SCHEMBL10813312 0.79 FAAH (0.45) ALDH1A1MAPTHTTL3MBTL1
SCHEMBL11759266 0.79 SMN1; SMN2 (0.40) CYP2D6KIF11MEN1KMT2ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109810572-A Inorganic nano material prints ink and its preparation method and application 深圳TCL工业研究院有限公司 2019-05-28 CN claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
CN-1238055-C Medicine for curing metabolic syndrome LIAONING YILIAN NEW MEDICINE I (CN) 2006-01-25 CN claimed
CN-1443575-A Medicine for curing metabolic syndrome LIAONING YILIAN NEW MEDICINE I (CN) 2003-09-24 CN claimed
CN-1433766-A Medicine for treating metabolism syndrome LIAONING YILIAN NOVEL MEDICINE (CN) 2003-08-06 CN claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-0179662-B1 FODDER ADDITIVE AND A PROCESS FOR THE PREPARATION THEREOF RICHTER GEDEON VEGYESZET (HU) 1990-10-03 EP claimed
US-4659712-A ELIMINATION OF METABOLITES FROM LIVER RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1987-04-21 US claimed
US-4039589-A LIVER MICROSOMAL ENZYMES RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1977-08-02 US claimed
EP-2841109-B1 PRODRUGS OF HYDROXYL-COMPRISING DRUGS ASCENDIS PHARMA AS (DK) 2026-04-15 EP disclosed
EP-4706683-A2 CHEWABLE FORMULATIONS Elanco Tiergesundheit AG (CH) 2026-03-11 EP disclosed
US-4094908-A Alpha-substituted benzhydrol derivatives RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1978-06-13 US disclosed
US-4039589-A LIVER MICROSOMAL ENZYMES RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1977-08-02 US disclosed